TARGET-GASTRO
Driving innovation in GI research through real-world evidence
Accelerating GI Research
TARGET-GASTRO is a comprehensive patient registry designed to advance gastrointestinal (GI) research. With a robust network of over 35 sites across the United States, the registry has enrolled over 39,000 patients with a variety of GI conditions. This diverse patient population reflects the demographics of the U.S., ensuring that the registry provides a valuable resource for understanding real-world disease progression, treatment patterns, and patient outcomes.
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35,000+ Patients
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35+ Sites
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20+ Publications
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10+ Clinical Investigators
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Partnership with the AGA
Complete Patient Journeys to Create a Fit-For-Purpose Dataset
Target RWE's real-world data offers a wealth of information that can be used to advance the understandings of gastrointestinal diseases. By analyzing patient-level data, researchers can gain valuable insights into disease progression, treatment efficacy, and patient outcomes.
Demographics
TARGET-GASTRO captures all demographics of patient populations, such as age, sex, and ethnicity, enabling researchers to identify trends, risk factors, and disparities in disease prevalence and outcomes.
Examples of Measures
Sex, race, ethnicity, birth year, three-digit ZIP, payer type, & years of education.
Vitals
Vital signs provide valuable insights into overall patient health and can help identify potential complications associated with GI conditions.
Examples of Measures
Height, weight, BMI & blood pressure
Medications
TARGET-GASTRO captures detailed information on prescribed medications, including dosage, duration of therapy, and adherence, and enables researchers to assess treatment effectiveness, identify adverse events, and evaluate drug interactions.
Examples of Measures
Medication name, dose, time on treatment, & discontinuation reason
Procedures
Procedural data, including endoscopy and other minimally invasive techniques, are essential for evaluating the functional changes and overall health of the GI tract. Data capture of colonoscopies and upper GI endoscopies allows for direct visualization of the GI lining, enabling the detection of abnormalities like inflammation, ulcers, or tumors.
This data also provides real-time information on the need for surgical interventions and helps guide treatment decisions, making them invaluable in diagnosing and managing GI conditions.
Examples of Measures
Blood transfusions, bowel resection, colonoscopy findings, & endoscopy findings
Imaging
Imaging studies, such as CT scans, MRIs, and ultrasounds, provide clinicians and researchers to monitor disease progression, identify complications, and evaluate the effectiveness of treatments. These visual tools enable early detection and intervention, significantly improving patient outcomes and reducing the need for more invasive procedures.
Examples of Measures
Type of imaging, perianal disease indication & location, strictures, abscess obstruction, fistula, & thickening
Labs
Laboratory tests, including blood tests and stool samples, provide critical information about a patient's health status. By analyzing lab results, researchers can identify biomarkers of disease activity, monitor treatment response, and assess the risk of complications.
Examples of Measures
CRP, fecal calprotectin, drug concentration, antibody levels
Disease Activity & Severity Scores
TARGET-GASTRO offers a source of rich unstructured & structured data for researchers that include a variety of disease activity and severity scores across multiple GI conditions, including Inflammatory Bowel Disease (IBD), Ulcerative Colitis (UC), Crohn’s Disease (CD), Eosinophilic Gastrointestinal Disorders (EGIDs), Clostridium difficile infection (C. diff), and Celiac Disease.
By utilizing these standardized disease activity scores researchers can assess the efficacy of new therapies, identify patient subgroups for targeted treatments, inform the design of clinical trials, and track long-term disease progression and potential complications.
Disease Severity Index
Mayo Endoscopic Score
UC Disease Activity Index
EREFs
Harvey Bradshaw Index
Simple Endoscopic Score for CD
EoE I-SEE Score
Modified Marsh Score
Crohn’s Disease Activity Index
Proud Partners with the American Gastroenterological Association (AGA)
Target RWE is committed to revolutionizing healthcare through real-world evidence. By partnering with leading organizations like the AGA, we are leveraging the power of real-world data to expand the data available for serious, and often chronic gastroenterological diseases to to accelerate drug development, improve patient outcomes, and address unmet medical needs.
With the strategic partnership between Target RWE and the AGA, we have incorporated the AGA's eosinophilic esophagitis (EoE) severity index tool, I-SEE, into the TARGET-GASTRO registry to assess EoE severity. This has enabled the collection of robust data on EoE patients, allowing researchers to track disease progression, compare treatment options, and ultimately improve the diagnosis and management of this chronic condition.
Learn moreCollaborating with TARGET-GASTRO
Advance Research in Gastroenterology
Be part of one of the largest and most dynamic networks dedicated to advancing GI science.
Connect with Leading Researchers & Use Powerful Analytical Tools
Collaborate with leading GI experts, leverage cutting-edge technologies, and play a pivotal role in driving innovation that shapes the future of clinical research in gastroenterology.
From Concept to Publication
TARGET-GASTRO offers resources to help you refine your observational-research initiatives and bring them to life.
Access Innovative Tools
Our cloud-based platform provides the analytics tools and data you need to conduct your research.
Discover Insights at Your Fingertips
Our Data Explorer Cohort Tool provides access to de-identified patient data to fuel your research initiatives.
Collaborate & Innovate
Use our tool to explore data, refine research questions, and identify potential study populations.
Ready to Partner with TARGET-GASTRO to Advance Gastrointestinal Research?
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